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P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium

To preserve epithelial barrier function, dying cells are squeezed out of an epithelium by “apoptotic cell extrusion.” Specifically, a cell destined for apoptosis signals its live neighboring epithelial cells to form and contract a ring of actin and myosin II that squeezes the dying cell out of the e...

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Detalles Bibliográficos
Autores principales: Slattum, Gloria, McGee, Karen M., Rosenblatt, Jody
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742179/
https://www.ncbi.nlm.nih.gov/pubmed/19720875
http://dx.doi.org/10.1083/jcb.200903079