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Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities

Homologous recombination (HR) is essential for faithful repair of DNA lesions yet must be kept in check, as unrestrained HR may compromise genome integrity and lead to premature aging or cancer. To limit unscheduled HR, cells possess DNA helicases capable of preventing excessive recombination. In th...

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Detalles Bibliográficos
Autores principales:	Fugger, Kasper, Mistrik, Martin, Danielsen, Jannie Rendtlew, Dinant, Christoffel, Falck, Jacob, Bartek, Jiri, Lukas, Jiri, Mailand, Niels
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742184/ https://www.ncbi.nlm.nih.gov/pubmed/19736316 http://dx.doi.org/10.1083/jcb.200812138

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