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Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments

To determine why the duration of mitosis (DM) is less in Taxol than in nocodazole or Eg5 inhibitors we studied the relationship between Taxol concentration, the DM, and the mitotic checkpoint. We found that unlike for other spindle poisons, in Taxol the DM becomes progressively shorter as the concen...

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Detalles Bibliográficos
Autores principales: Yang, Zhenye, Kenny, Alison E., Brito, Daniela A., Rieder, Conly L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742195/
https://www.ncbi.nlm.nih.gov/pubmed/19720871
http://dx.doi.org/10.1083/jcb.200906150