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Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments
To determine why the duration of mitosis (DM) is less in Taxol than in nocodazole or Eg5 inhibitors we studied the relationship between Taxol concentration, the DM, and the mitotic checkpoint. We found that unlike for other spindle poisons, in Taxol the DM becomes progressively shorter as the concen...
Autores principales: | Yang, Zhenye, Kenny, Alison E., Brito, Daniela A., Rieder, Conly L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742195/ https://www.ncbi.nlm.nih.gov/pubmed/19720871 http://dx.doi.org/10.1083/jcb.200906150 |
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