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SHARE: an adaptive algorithm to select the most informative set of SNPs for candidate genetic association

Association studies have been widely used to identify genetic liability variants for complex diseases. While scanning the chromosomal region 1 single nucleotide polymorphism (SNP) at a time may not fully explore linkage disequilibrium, haplotype analyses tend to require a fairly large number of para...

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Detalles Bibliográficos
Autores principales: Dai, James Y., Leblanc, Michael, Smith, Nicholas L., Psaty, Bruce, Kooperberg, Charles
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742496/
https://www.ncbi.nlm.nih.gov/pubmed/19605740
http://dx.doi.org/10.1093/biostatistics/kxp023