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Heme Regulatory Motifs in Heme Oxygenase-2 Form a Thiol/Disulfide Redox Switch That Responds to the Cellular Redox State

Heme oxygenase (HO) catalyzes the rate-limiting step in heme catabolism to generate CO, biliverdin, and free iron. Two isoforms of HO have been identified in mammals: inducible HO-1 and constitutively expressed HO-2. HO-1 and HO-2 share similar physical and kinetic properties but have different phys...

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Detalles Bibliográficos
Autores principales:	Yi, Li, Jenkins, Paul M., Leichert, Lars I., Jakob, Ursula, Martens, Jeffrey R., Ragsdale, Stephen W.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Enzyme Catalysis and Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742820/ https://www.ncbi.nlm.nih.gov/pubmed/19473966 http://dx.doi.org/10.1074/jbc.M109.015651

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