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Identification by Automated Screening of a Small Molecule that Selectively Eliminates Neural Stem Cells Derived from hESCs but Not Dopamine Neurons
BACKGROUND: We have previously described fundamental differences in the biology of stem cells as compared to other dividing cell populations. We reasoned therefore that a differential screen using US Food and Drug Administration (FDA)-approved compounds may identify either selective survival factors...
Autores principales: | Han, Yi, Miller, Aaron, Mangada, Julie, Liu, Ying, Swistowski, Andrzej, Zhan, Ming, Rao, Mahendra S., Zeng, Xianmin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743191/ https://www.ncbi.nlm.nih.gov/pubmed/19774075 http://dx.doi.org/10.1371/journal.pone.0007155 |
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