Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas

BACKGROUND: Malignant gliomas are the most prevalent type of primary brain tumours but the therapeutic armamentarium for these tumours is limited. Platelet-derived growth factor (PDGF) signalling has been shown to be a key regulator of glioma development. Clinical trials evaluating the efficacy of a...

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Detalles Bibliográficos
Autores principales: Martinho, O, Longatto-Filho, A, Lambros, M B K, Martins, A, Pinheiro, C, Silva, A, Pardal, F, Amorim, J, Mackay, A, Milanezi, F, Tamber, N, Fenwick, K, Ashworth, A, Reis-Filho, J S, Lopes, J M, Reis, R M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743351/
https://www.ncbi.nlm.nih.gov/pubmed/19707201
http://dx.doi.org/10.1038/sj.bjc.6605225

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