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Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane

BACKGROUND: Considerable interest lies in the identification of novel anti-angiogenic compounds for cancer therapy. We have investigated whether dexrazoxane has anti-angiogenic properties and if so, the mechanism of the inhibition. METHODS: The phenotypic effects of dexrazoxane on endothelial cell b...

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Detalles Bibliográficos
Autores principales:	Maloney, S L, Sullivan, D C, Suchting, S, Herbert, J M J, Rabai, E M, Nagy, Z, Barker, J, Sundar, S, Bicknell, R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743367/ https://www.ncbi.nlm.nih.gov/pubmed/19738618 http://dx.doi.org/10.1038/sj.bjc.6605203

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