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Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements
BACKGROUND: In eukaryotes, RNA interference (RNAi) is a major mechanism of defense against viruses and transposable elements as well of regulating translation of endogenous mRNAs. The RNAi systems recognize the target RNA molecules via small guide RNAs that are completely or partially complementary...
Autores principales: | Makarova, Kira S, Wolf, Yuri I, van der Oost, John, Koonin, Eugene V |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743648/ https://www.ncbi.nlm.nih.gov/pubmed/19706170 http://dx.doi.org/10.1186/1745-6150-4-29 |
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