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Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements

BACKGROUND: In eukaryotes, RNA interference (RNAi) is a major mechanism of defense against viruses and transposable elements as well of regulating translation of endogenous mRNAs. The RNAi systems recognize the target RNA molecules via small guide RNAs that are completely or partially complementary...

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Detalles Bibliográficos
Autores principales: Makarova, Kira S, Wolf, Yuri I, van der Oost, John, Koonin, Eugene V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743648/
https://www.ncbi.nlm.nih.gov/pubmed/19706170
http://dx.doi.org/10.1186/1745-6150-4-29

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