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Parallel Routes of Human Carcinoma Development: Implications of the Age-Specific Incidence Data
BACKGROUND: The multi-stage hypothesis suggests that cancers develop through a single defined series of genetic alterations. This hypothesis was first suggested over 50 years ago based upon age-specific incidence data. However, recent molecular studies of tumors indicate that multiple routes exist t...
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743810/ https://www.ncbi.nlm.nih.gov/pubmed/19774079 http://dx.doi.org/10.1371/journal.pone.0007053 |