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Myc-regulated microRNAs attenuate embryonic stem cell differentiation
Myc proteins are known to have an important function in stem cell maintenance. As Myc has been shown earlier to regulate microRNAs (miRNAs) involved in proliferation, we sought to determine whether c-Myc also affects embryonic stem (ES) cell maintenance and differentiation through miRNAs. Using a qu...
Autores principales: | Lin, Chin-Hsing, Jackson, Aimee L, Guo, Jie, Linsley, Peter S, Eisenman, Robert N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744176/ https://www.ncbi.nlm.nih.gov/pubmed/19745813 http://dx.doi.org/10.1038/emboj.2009.254 |
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