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Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy

We determined the prevalence of infection with lymphocytic choriomeningitis virus (LCMV) among small mammals in northern Italy and analyzed long-term dynamics of LCMV in a rodent population in the province of Trento. LCMV is circulating among the most widespread and common wild rodent species in thi...

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Autores principales: Tagliapietra, Valentina, Rosà, Roberto, Hauffe, Heidi C., Laakkonen, Juha, Voutilainen, Liina, Vapalahti, Olli, Vaheri, Antti, Henttonen, Heikki, Rizzoli, Annapaola
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744257/
https://www.ncbi.nlm.nih.gov/pubmed/19624914
http://dx.doi.org/10.3201/eid1507.081524
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author Tagliapietra, Valentina
Rosà, Roberto
Hauffe, Heidi C.
Laakkonen, Juha
Voutilainen, Liina
Vapalahti, Olli
Vaheri, Antti
Henttonen, Heikki
Rizzoli, Annapaola
author_facet Tagliapietra, Valentina
Rosà, Roberto
Hauffe, Heidi C.
Laakkonen, Juha
Voutilainen, Liina
Vapalahti, Olli
Vaheri, Antti
Henttonen, Heikki
Rizzoli, Annapaola
author_sort Tagliapietra, Valentina
collection PubMed
description We determined the prevalence of infection with lymphocytic choriomeningitis virus (LCMV) among small mammals in northern Italy and analyzed long-term dynamics of LCMV in a rodent population in the province of Trento. LCMV is circulating among the most widespread and common wild rodent species in this area (Apodemus flavicollis, Myodes glareolus, and Microtus arvalis); overall prevalence is 6.8%. During 2000–2006, intensive monitoring of LCMV in a population of yellow-necked mice (A. flavicollis) showed a positive correlation between prevalence of infection and rodent density. At the individual level, weight and sex appeared to correlate with antibody prevalence, which suggests that horizontal transmission of LCMV occurs principally among heavier, older males and occurs during fighting. Isolation and genetic characterization of this virus will be the crucial next steps for a better understanding of its ecology.
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spelling pubmed-27442572009-10-05 Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy Tagliapietra, Valentina Rosà, Roberto Hauffe, Heidi C. Laakkonen, Juha Voutilainen, Liina Vapalahti, Olli Vaheri, Antti Henttonen, Heikki Rizzoli, Annapaola Emerg Infect Dis Research We determined the prevalence of infection with lymphocytic choriomeningitis virus (LCMV) among small mammals in northern Italy and analyzed long-term dynamics of LCMV in a rodent population in the province of Trento. LCMV is circulating among the most widespread and common wild rodent species in this area (Apodemus flavicollis, Myodes glareolus, and Microtus arvalis); overall prevalence is 6.8%. During 2000–2006, intensive monitoring of LCMV in a population of yellow-necked mice (A. flavicollis) showed a positive correlation between prevalence of infection and rodent density. At the individual level, weight and sex appeared to correlate with antibody prevalence, which suggests that horizontal transmission of LCMV occurs principally among heavier, older males and occurs during fighting. Isolation and genetic characterization of this virus will be the crucial next steps for a better understanding of its ecology. Centers for Disease Control and Prevention 2009-07 /pmc/articles/PMC2744257/ /pubmed/19624914 http://dx.doi.org/10.3201/eid1507.081524 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Tagliapietra, Valentina
Rosà, Roberto
Hauffe, Heidi C.
Laakkonen, Juha
Voutilainen, Liina
Vapalahti, Olli
Vaheri, Antti
Henttonen, Heikki
Rizzoli, Annapaola
Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy
title Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy
title_full Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy
title_fullStr Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy
title_full_unstemmed Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy
title_short Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy
title_sort spatial and temporal dynamics of lymphocytic choriomeningitis virus in wild rodents, northern italy
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744257/
https://www.ncbi.nlm.nih.gov/pubmed/19624914
http://dx.doi.org/10.3201/eid1507.081524
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