Loss of ATRX in Chondrocytes Has Minimal Effects on Skeletal Development

BACKGROUND: Mutations in the human ATRX gene cause developmental defects, including skeletal deformities and dwarfism. ATRX encodes a chromatin remodeling protein, however the role of ATRX in skeletal development is currently unknown. METHODOLOGY/PRINCIPAL FINDINGS: We induced Atrx deletion in mouse...

Descripción completa

Detalles Bibliográficos
Autores principales: Solomon, Lauren A., Li, Jennifer R., Bérubé, Nathalie G., Beier, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744333/
https://www.ncbi.nlm.nih.gov/pubmed/19774083
http://dx.doi.org/10.1371/journal.pone.0007106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744333/
https://www.ncbi.nlm.nih.gov/pubmed/19774083
http://dx.doi.org/10.1371/journal.pone.0007106

Ejemplares similares