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Loss of ATRX in Chondrocytes Has Minimal Effects on Skeletal Development

BACKGROUND: Mutations in the human ATRX gene cause developmental defects, including skeletal deformities and dwarfism. ATRX encodes a chromatin remodeling protein, however the role of ATRX in skeletal development is currently unknown. METHODOLOGY/PRINCIPAL FINDINGS: We induced Atrx deletion in mouse...

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Detalles Bibliográficos
Autores principales:	Solomon, Lauren A., Li, Jennifer R., Bérubé, Nathalie G., Beier, Frank
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744333/ https://www.ncbi.nlm.nih.gov/pubmed/19774083 http://dx.doi.org/10.1371/journal.pone.0007106

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