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Human Telomerase Reverse Transcriptase (hTERT) Q169 Is Essential for Telomerase Function In Vitro and In Vivo

BACKGROUND: Telomerase is a reverse transcriptase that maintains the telomeres of linear chromosomes and preserves genomic integrity. The core components are a catalytic protein subunit, the telomerase reverse transcriptase (TERT), and an RNA subunit, the telomerase RNA (TR). Telomerase is unique in...

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Detalles Bibliográficos
Autores principales:	Wyatt, Haley D. M., Tsang, Allison R., Lobb, Deirdre A., Beattie, Tara L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744565/ https://www.ncbi.nlm.nih.gov/pubmed/19777057 http://dx.doi.org/10.1371/journal.pone.0007176

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