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Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane
BACKGROUND: The spread of drug resistance has been a major obstacle to the control of malaria. The mechanisms underlying drug resistance in malaria seem to be complex and multigenic. The current literature on multiple drug resistance against anti-malarials has documented PfMDR1, an ATP-binding casse...
Autores principales: | Kavishe, Reginald A, van den Heuvel, Jeroen MW, van de Vegte-Bolmer, Marga, Luty, Adrian JF, Russel, Frans GM, Koenderink, Jan B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744701/ https://www.ncbi.nlm.nih.gov/pubmed/19715599 http://dx.doi.org/10.1186/1475-2875-8-205 |
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