An integrated approach to the interpretation of Single Amino Acid Polymorphisms within the framework of CATH and Gene3D

BACKGROUND: The phenotypic effects of sequence variations in protein-coding regions come about primarily via their effects on the resulting structures, for example by disrupting active sites or affecting structural stability. In order better to understand the mechanisms behind known mutant phenotype...

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Detalles Bibliográficos
Autores principales: Izarzugaza, Jose MG, Baresic, Anja, McMillan, Lisa EM, Yeats, Corin, Clegg, Andrew B, Orengo, Christine A, Martin, Andrew CR, Valencia, Alfonso
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745587/
https://www.ncbi.nlm.nih.gov/pubmed/19758469
http://dx.doi.org/10.1186/1471-2105-10-S8-S5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745587/
https://www.ncbi.nlm.nih.gov/pubmed/19758469
http://dx.doi.org/10.1186/1471-2105-10-S8-S5

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