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An integrated approach to the interpretation of Single Amino Acid Polymorphisms within the framework of CATH and Gene3D
BACKGROUND: The phenotypic effects of sequence variations in protein-coding regions come about primarily via their effects on the resulting structures, for example by disrupting active sites or affecting structural stability. In order better to understand the mechanisms behind known mutant phenotype...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745587/ https://www.ncbi.nlm.nih.gov/pubmed/19758469 http://dx.doi.org/10.1186/1471-2105-10-S8-S5 |