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From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathways
BACKGROUND: Single nucleotide polymorphisms (SNPs) are the most frequent type of sequence variation between individuals, and represent a promising tool for finding genetic determinants of complex diseases and understanding the differences in drug response. In this regard, it is of particular interes...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745588/ https://www.ncbi.nlm.nih.gov/pubmed/19758470 http://dx.doi.org/10.1186/1471-2105-10-S8-S6 |