Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes

Genomic regulatory blocks are chromosomal regions spanned by long clusters of highly conserved noncoding elements devoted to long-range regulation of developmental genes, often immobilizing other, unrelated genes into long-lasting syntenic arrangements. Synorth is a web resource for exploring and ca...

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Detalles Bibliográficos
Autores principales: Dong, Xianjun, Fredman, David, Lenhard, Boris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745767/
https://www.ncbi.nlm.nih.gov/pubmed/19698106
http://dx.doi.org/10.1186/gb-2009-10-8-r86
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author Dong, Xianjun
Fredman, David
Lenhard, Boris
author_facet Dong, Xianjun
Fredman, David
Lenhard, Boris
author_sort Dong, Xianjun
collection PubMed
description Genomic regulatory blocks are chromosomal regions spanned by long clusters of highly conserved noncoding elements devoted to long-range regulation of developmental genes, often immobilizing other, unrelated genes into long-lasting syntenic arrangements. Synorth is a web resource for exploring and categorizing the syntenic relationships in genomic regulatory blocks across multiple genomes, tracing their evolutionary fate after teleost whole genome duplication at the level of genomic regulatory block loci, individual genes, and their phylogenetic context.
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spelling pubmed-27457672009-09-17 Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes Dong, Xianjun Fredman, David Lenhard, Boris Genome Biol Software Genomic regulatory blocks are chromosomal regions spanned by long clusters of highly conserved noncoding elements devoted to long-range regulation of developmental genes, often immobilizing other, unrelated genes into long-lasting syntenic arrangements. Synorth is a web resource for exploring and categorizing the syntenic relationships in genomic regulatory blocks across multiple genomes, tracing their evolutionary fate after teleost whole genome duplication at the level of genomic regulatory block loci, individual genes, and their phylogenetic context. BioMed Central 2009 2009-08-21 /pmc/articles/PMC2745767/ /pubmed/19698106 http://dx.doi.org/10.1186/gb-2009-10-8-r86 Text en Copyright © 2009 Dong et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
spellingShingle Software
Dong, Xianjun
Fredman, David
Lenhard, Boris
Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes
title Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes
title_full Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes
title_fullStr Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes
title_full_unstemmed Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes
title_short Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes
title_sort synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745767/
https://www.ncbi.nlm.nih.gov/pubmed/19698106
http://dx.doi.org/10.1186/gb-2009-10-8-r86
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AT fredmandavid synorthexploringtheevolutionofsyntenyandlongrangeregulatoryinteractionsinvertebrategenomes
AT lenhardboris synorthexploringtheevolutionofsyntenyandlongrangeregulatoryinteractionsinvertebrategenomes

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