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Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?

An association between high levels of serum urate and cardiovascular disease has been proposed for many decades. However, it was only recently that compelling basic science data, small clinical trials, and epidemiological studies have provided support to the idea of a true causal effect. In this rev...

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Detalles Bibliográficos
Autores principales: Gaffo, Angelo L, Edwards, N Lawrence, Saag, Kenneth G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745789/
https://www.ncbi.nlm.nih.gov/pubmed/19725932
http://dx.doi.org/10.1186/ar2761
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author Gaffo, Angelo L
Edwards, N Lawrence
Saag, Kenneth G
author_facet Gaffo, Angelo L
Edwards, N Lawrence
Saag, Kenneth G
author_sort Gaffo, Angelo L
collection PubMed
description An association between high levels of serum urate and cardiovascular disease has been proposed for many decades. However, it was only recently that compelling basic science data, small clinical trials, and epidemiological studies have provided support to the idea of a true causal effect. In this review we present recently published data that study the association between hyperuricemia and selected cardiovascular diseases, with a final conclusion about the possibility of this association being causal.
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spelling pubmed-27457892010-02-19 Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link? Gaffo, Angelo L Edwards, N Lawrence Saag, Kenneth G Arthritis Res Ther Review An association between high levels of serum urate and cardiovascular disease has been proposed for many decades. However, it was only recently that compelling basic science data, small clinical trials, and epidemiological studies have provided support to the idea of a true causal effect. In this review we present recently published data that study the association between hyperuricemia and selected cardiovascular diseases, with a final conclusion about the possibility of this association being causal. BioMed Central 2009 2009-08-19 /pmc/articles/PMC2745789/ /pubmed/19725932 http://dx.doi.org/10.1186/ar2761 Text en Copyright © 2009 BioMed Central Ltd
spellingShingle Review
Gaffo, Angelo L
Edwards, N Lawrence
Saag, Kenneth G
Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?
title Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?
title_full Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?
title_fullStr Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?
title_full_unstemmed Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?
title_short Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?
title_sort gout. hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745789/
https://www.ncbi.nlm.nih.gov/pubmed/19725932
http://dx.doi.org/10.1186/ar2761
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