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The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model
BACKGROUND: The secretory basic amino acid-specific proprotein convertases (PCs) have often been associated with cancer/metastasis. By controlling the cleavage of cancer-associated proteins, PCs play key roles in multiple steps of cancer development. Most analyses of the implication of PCs in cancer...
Autores principales: | Sun, Xiaowei, Essalmani, Rachid, Seidah, Nabil G, Prat, Annik |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746178/ https://www.ncbi.nlm.nih.gov/pubmed/19737405 http://dx.doi.org/10.1186/1476-4598-8-73 |
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