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Normal RNAi response in human fragile × fibroblasts
BACKGROUND: Fragile × syndrome is caused by loss of expression of the FMRP protein involved in the control of a large number of mRNA targets. The Drosophila ortholog dFXR interacts with a protein complex that includes Argonaute2, an essential component of the RNA-induced silencing complex (RISC). Fu...
Autores principales: | Madsen, Charlotte, Grønskov, Karen, Brøndum-Nielsen, Karen, Jensen, Thomas G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746233/ https://www.ncbi.nlm.nih.gov/pubmed/19740428 http://dx.doi.org/10.1186/1756-0500-2-177 |
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