Arginine methylation of Piwi proteins, catalyzed by dPRMT5, is required for Ago3 and Aub stability

Piwi family proteins are essential for germline development and bind piwi-interacting RNAs (piRNAs 1 2 3). The grandchildless gene aub of Drosophila melanogaster encodes the piRNA-binding protein Aub that is essential for formation of primordial germ cells (PGCs) 4. Here we report that mouse, Xenopu...

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Detalles Bibliográficos
Autores principales: Kirino, Yohei, Kim, Namwoo, de Planell-Saguer, Mariàngels, Khandros, Eugene, Chiorean, Stephanie, Klein, Peter S., Rigoutsos, Isidore, Jongens, Thomas A., Mourelatos, Zissimos
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746449/
https://www.ncbi.nlm.nih.gov/pubmed/19377467
http://dx.doi.org/10.1038/ncb1872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746449/
https://www.ncbi.nlm.nih.gov/pubmed/19377467
http://dx.doi.org/10.1038/ncb1872

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