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Arginine methylation of Piwi proteins, catalyzed by dPRMT5, is required for Ago3 and Aub stability
Piwi family proteins are essential for germline development and bind piwi-interacting RNAs (piRNAs 1 2 3). The grandchildless gene aub of Drosophila melanogaster encodes the piRNA-binding protein Aub that is essential for formation of primordial germ cells (PGCs) 4. Here we report that mouse, Xenopu...
Autores principales: | Kirino, Yohei, Kim, Namwoo, de Planell-Saguer, Mariàngels, Khandros, Eugene, Chiorean, Stephanie, Klein, Peter S., Rigoutsos, Isidore, Jongens, Thomas A., Mourelatos, Zissimos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746449/ https://www.ncbi.nlm.nih.gov/pubmed/19377467 http://dx.doi.org/10.1038/ncb1872 |
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