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Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden
We investigated effects of occupational physical activity on relative risk for prostate cancer. From Swedish nationwide censuses in 1960 and 1970, we defined two cohorts of men whose occupational titles allowed classification of physical activity levels at work in 1960 (n=1 348 971) and in 1970 (n=1...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746533/ https://www.ncbi.nlm.nih.gov/pubmed/11857014 http://dx.doi.org/10.1038/sj.bjc.6600023 |
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author | Norman, A Moradi, T Gridley, G Dosemeci, M Rydh, B Nyrén, O Wolk, A |
author_facet | Norman, A Moradi, T Gridley, G Dosemeci, M Rydh, B Nyrén, O Wolk, A |
author_sort | Norman, A |
collection | PubMed |
description | We investigated effects of occupational physical activity on relative risk for prostate cancer. From Swedish nationwide censuses in 1960 and 1970, we defined two cohorts of men whose occupational titles allowed classification of physical activity levels at work in 1960 (n=1 348 971) and in 1970 (n=1 377 629). A third cohort included only men whose jobs required a similar level of physical activity in both 1960 and 1970 (n=673 443). The incidence of prostate cancer between 1971 and 1989 was ascertained through record linkage to the Swedish Cancer Register. A total of 43 836, 28 702, and 19 670 prostate cancers, respectively, occurred in the three cohorts. In all three cohorts, the relative risk for prostate cancer increased with decreasing level of occupational physical activity (P<0.001), using Poisson regression. Among men with the same physical activity levels in 1960 and 1970, the rate ratio was 1.11 for men with sedentary jobs as compared with those whose jobs had very high/high activity levels after adjustment for age at follow-up, calendar year of follow-up and place of residence (95% CI 1.05–1.17; P for trend <0.001). There was no association between occupational activity and prostate cancer mortality. Since we had no data on other potential risk factors the observed associations for both incidence and mortality might have been confounded. Further studies are needed to better understand the potential role of physical activity for prostate cancer. British Journal of Cancer (2002) 86, 70–75. DOI: 10.1038/sj/bjc/6600023 www.bjcancer.com © 2002 The Cancer Research Campaign |
format | Text |
id | pubmed-2746533 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-27465332009-09-18 Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden Norman, A Moradi, T Gridley, G Dosemeci, M Rydh, B Nyrén, O Wolk, A Br J Cancer Epidemiology We investigated effects of occupational physical activity on relative risk for prostate cancer. From Swedish nationwide censuses in 1960 and 1970, we defined two cohorts of men whose occupational titles allowed classification of physical activity levels at work in 1960 (n=1 348 971) and in 1970 (n=1 377 629). A third cohort included only men whose jobs required a similar level of physical activity in both 1960 and 1970 (n=673 443). The incidence of prostate cancer between 1971 and 1989 was ascertained through record linkage to the Swedish Cancer Register. A total of 43 836, 28 702, and 19 670 prostate cancers, respectively, occurred in the three cohorts. In all three cohorts, the relative risk for prostate cancer increased with decreasing level of occupational physical activity (P<0.001), using Poisson regression. Among men with the same physical activity levels in 1960 and 1970, the rate ratio was 1.11 for men with sedentary jobs as compared with those whose jobs had very high/high activity levels after adjustment for age at follow-up, calendar year of follow-up and place of residence (95% CI 1.05–1.17; P for trend <0.001). There was no association between occupational activity and prostate cancer mortality. Since we had no data on other potential risk factors the observed associations for both incidence and mortality might have been confounded. Further studies are needed to better understand the potential role of physical activity for prostate cancer. British Journal of Cancer (2002) 86, 70–75. DOI: 10.1038/sj/bjc/6600023 www.bjcancer.com © 2002 The Cancer Research Campaign Nature Publishing Group 2002-01-07 /pmc/articles/PMC2746533/ /pubmed/11857014 http://dx.doi.org/10.1038/sj.bjc.6600023 Text en Copyright © 2002 The Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Epidemiology Norman, A Moradi, T Gridley, G Dosemeci, M Rydh, B Nyrén, O Wolk, A Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden |
title | Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden |
title_full | Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden |
title_fullStr | Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden |
title_full_unstemmed | Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden |
title_short | Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden |
title_sort | occupational physical activity and risk for prostate cancer in a nationwide cohort study in sweden |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746533/ https://www.ncbi.nlm.nih.gov/pubmed/11857014 http://dx.doi.org/10.1038/sj.bjc.6600023 |
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