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Anti-angiogenic action of hyperthermia by suppressing gene expression and production of tumour-derived vascular endothelial growth factor in vivo and in vitro

Vascular endothelial growth factor is an important angiogenic factor for tumour progression because it increases endothelial-cell proliferation and remodels extracellular matrix in blood vessels. We demonstrated that hyperthermia at 42°C, termed heat shock, suppressed the gene expression and product...

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Detalles Bibliográficos
Autores principales: Sawaji, Y, Sato, T, Takeuchi, A, Hirata, M, Ito, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746582/
https://www.ncbi.nlm.nih.gov/pubmed/12085210
http://dx.doi.org/10.1038/sj.bjc.6600268

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