Generation of dendritic cell-based vaccines for cancer therapy

Dendritic cells play a major role in the generation of immunity against tumour cells. They can be grown under various culture conditions, which influence the phenotypical and functional properties of dendritic cells and thereby the consecutive immune response mainly executed by T cells. Here we disc...

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Autores principales: Reinhard, G, Märten, A, Kiske, S M, Feil, F, Bieber, T, Schmidt-Wolf, I G H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746586/
https://www.ncbi.nlm.nih.gov/pubmed/12085199
http://dx.doi.org/10.1038/sj.bjc.6600316
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author Reinhard, G
Märten, A
Kiske, S M
Feil, F
Bieber, T
Schmidt-Wolf, I G H
author_facet Reinhard, G
Märten, A
Kiske, S M
Feil, F
Bieber, T
Schmidt-Wolf, I G H
author_sort Reinhard, G
collection PubMed
description Dendritic cells play a major role in the generation of immunity against tumour cells. They can be grown under various culture conditions, which influence the phenotypical and functional properties of dendritic cells and thereby the consecutive immune response mainly executed by T cells. Here we discuss various conditions, which are important during generation and administration of dendritic cells to elicit a tumouricidal T cell-based immune response. British Journal of Cancer (2002) 86, 1529–1533. DOI: 10.1038/sj/bjc/6600316 www.bjcancer.com © 2002 Cancer Research UK
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spelling pubmed-27465862009-09-18 Generation of dendritic cell-based vaccines for cancer therapy Reinhard, G Märten, A Kiske, S M Feil, F Bieber, T Schmidt-Wolf, I G H Br J Cancer Minireview Dendritic cells play a major role in the generation of immunity against tumour cells. They can be grown under various culture conditions, which influence the phenotypical and functional properties of dendritic cells and thereby the consecutive immune response mainly executed by T cells. Here we discuss various conditions, which are important during generation and administration of dendritic cells to elicit a tumouricidal T cell-based immune response. British Journal of Cancer (2002) 86, 1529–1533. DOI: 10.1038/sj/bjc/6600316 www.bjcancer.com © 2002 Cancer Research UK Nature Publishing Group 2002-05-20 2002-05-03 /pmc/articles/PMC2746586/ /pubmed/12085199 http://dx.doi.org/10.1038/sj.bjc.6600316 Text en Copyright © 2002 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Reinhard, G
Märten, A
Kiske, S M
Feil, F
Bieber, T
Schmidt-Wolf, I G H
Generation of dendritic cell-based vaccines for cancer therapy
title Generation of dendritic cell-based vaccines for cancer therapy
title_full Generation of dendritic cell-based vaccines for cancer therapy
title_fullStr Generation of dendritic cell-based vaccines for cancer therapy
title_full_unstemmed Generation of dendritic cell-based vaccines for cancer therapy
title_short Generation of dendritic cell-based vaccines for cancer therapy
title_sort generation of dendritic cell-based vaccines for cancer therapy
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746586/
https://www.ncbi.nlm.nih.gov/pubmed/12085199
http://dx.doi.org/10.1038/sj.bjc.6600316
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