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Single-feature polymorphism discovery by computing probe affinity shape powers

BACKGROUND: Single-feature polymorphism (SFP) discovery is a rapid and cost-effective approach to identify DNA polymorphisms. However, high false positive rates and/or low sensitivity are prevalent in previously described SFP detection methods. This work presents a new computing method for SFP disco...

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Detalles Bibliográficos
Autores principales: Xu, Wayne Wenzhong, Cho, Seungho, Yang, S Samuel, Bolon, Yung-Tsi, Bilgic, Hatice, Jia, Haiyan, Xiong, Yanwen, Muehlbauer, Gary J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746803/
https://www.ncbi.nlm.nih.gov/pubmed/19709416
http://dx.doi.org/10.1186/1471-2156-10-48