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Single molecule conformational analysis of DNA G-quadruplexes

Single molecule fluorescence resonance energy transfer (FRET) can be employed to study conformational heterogeneity and real-time dynamics of biological macromolecules. Here we present single molecule studies on human genomic DNA G-quadruplex sequences that occur in the telomeres and in the promoter...

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Detalles Bibliográficos
Autores principales: Shirude, Pravin S., Balasubramanian, Shankar
Formato: Texto
Lenguaje:English
Publicado: Editions Scientifiques Elsevier 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746965/
https://www.ncbi.nlm.nih.gov/pubmed/18295608
http://dx.doi.org/10.1016/j.biochi.2008.01.015