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Global Transcriptional Response to Hfe Deficiency and Dietary Iron Overload in Mouse Liver and Duodenum
Iron is an essential trace element whose absorption is usually tightly regulated in the duodenum. HFE-related hereditary hemochromatosis (HH) is characterized by abnormally low expression of the iron-regulatory hormone, hepcidin, which results in increased iron absorption. The liver is crucial for i...
Autores principales: | Rodriguez, Alejandra, Luukkaala, Tiina, Fleming, Robert E., Britton, Robert S., Bacon, Bruce R., Parkkila, Seppo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747280/ https://www.ncbi.nlm.nih.gov/pubmed/19787063 http://dx.doi.org/10.1371/journal.pone.0007212 |
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