Direct Activation of Protein Kinases by Unanchored Polyubiquitin Chains

TRAF6 is a ubiquitin ligase essential for the activation of NF-κB and MAP kinases in multiple signaling pathways including those emanating from the interleukin-1 and Toll-like receptors (IL-1R/TLR)1-3. TRAF6 functions together with a ubiquitin-conjugating enzyme complex consisting of Ubc13 and Uev1A...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Zong-Ping, Sun, Lijun, Chen, Xiang, Pineda, Gabriel, Jiang, Xiaomo, Adhikari, Anirban, Zeng, Wenwen, Chen, Zhijian J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747300/
https://www.ncbi.nlm.nih.gov/pubmed/19675569
http://dx.doi.org/10.1038/nature08247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747300/
https://www.ncbi.nlm.nih.gov/pubmed/19675569
http://dx.doi.org/10.1038/nature08247

Ejemplares similares