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Current use and potential role of bevacizumab in the treatment of gastrointestinal cancers

Angiogenesis is essential for cancer growth and metastasis. Vascular endothelial growth factor (VEGF) is a key modulator of angiogenesis. In addition, overexpression of VEGF is correlated with advanced disease and poor prognosis. Bevacizumab, a recombinant humanized anti-VEGF monoclonal antibody, is...

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Detalles Bibliográficos
Autores principales:	Li, Jia, Saif, Muhammad Wasif
Formato:	Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2009
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747341/ https://www.ncbi.nlm.nih.gov/pubmed/19774210

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