In vivo biodistribution of a highly attenuated recombinant vesicular stomatitis virus expressing HIV-1 Gag following intramuscular, intranasal, or intravenous inoculation

Recombinant vesicular stomatitis viruses (rVSVs) are being developed as potential HIV-1 vaccine candidates. To characterize the in vivo replication and dissemination of rVSV vectors in mice, high doses of a highly attenuated vector expressing HIV-1 Gag, rVSV(IN)-N4CT9-Gag1, and a prototypic referenc...

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Detalles Bibliográficos
Autores principales: Erik Johnson, J., Coleman, John W., Kalyan, Narender K., Calderon, Priscilla, Wright, Kevin J., Obregon, Jennifer, Ogin-Wilson, Eleanor, Natuk, Robert J., Clarke, David K., Udem, Stephen A., Cooper, David, Michael Hendry, R.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Ltd. Published by Elsevier Ltd. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747378/
https://www.ncbi.nlm.nih.gov/pubmed/19428903
http://dx.doi.org/10.1016/j.vaccine.2009.03.006

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