BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

Germline mutations of the tumour suppressor gene BRCA1 are involved in the predisposition and development of breast cancer and account for 20–45% of all hereditary cases. There is an increasing evidence that these tumours are characterised by a specific phenotype and pattern of gene expression. We h...

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Detalles Bibliográficos
Autores principales: Tassone, P, Tagliaferri, P, Perricelli, A, Blotta, S, Quaresima, B, Martelli, M L, Goel, A, Barbieri, V, Costanzo, F, Boland, C R, Venuta, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747554/
https://www.ncbi.nlm.nih.gov/pubmed/12698198
http://dx.doi.org/10.1038/sj.bjc.6600859

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