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Redirecting mouse T hybridoma against human breast and ovarian carcinomas: in vivo activity against HER-2/neu expressing cancer cells

Chimeric receptors comprising of the T-cell receptor-ζ cytoplasmic signalling chain fused to an extracellular ligand-binding domain of a single-chain antibody (scFv) have served as effective tools for redirecting cytotoxic T lymphocytes (CTL) against tumour cells. In this report, we constructed a ch...

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Detalles Bibliográficos
Autores principales:	Gritzapis, A D, Mamalaki, A, Kretsovali, A, Papamatheakis, J, Belimezi, M, Perez, S A, Baxevanis, C N, Papamichail, M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747561/ https://www.ncbi.nlm.nih.gov/pubmed/12698199 http://dx.doi.org/10.1038/sj.bjc.6600888

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