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Antitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cells
Cyclin-dependent kinase inhibitors (CDKIs) are considered as novel anticancer agents because of their ability to induce growth arrest or apoptosis in tumour cells. It has not yet been fully determined, however, which CDKI is the best candidate for the treatment of malignant gliomas and whether norma...
Autores principales: | Komata, T, Kanzawa, T, Takeuchi, H, Germano, I M, Schreiber, M, Kondo, Y, Kondo, S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747579/ https://www.ncbi.nlm.nih.gov/pubmed/12698196 http://dx.doi.org/10.1038/sj.bjc.6600862 |
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