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Alternative Splicing of TCF7L2 Gene in Omental and Subcutaneous Adipose Tissue and Risk of Type 2 Diabetes

BACKGROUND: Single nucleotide polymorphisms (SNPs) rs7903146 and rs12255372 located within TCF7L2 gene have been identified as the strongest common genetic risk factors for development of type 2 diabetes (T2D). We hypothesized that these genetic variants might increase the risk of T2D through regula...

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Detalles Bibliográficos
Autores principales: Prokunina-Olsson, Ludmila, Kaplan, Lee M., Schadt, Eric E., Collins, Francis S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747626/
https://www.ncbi.nlm.nih.gov/pubmed/19789636
http://dx.doi.org/10.1371/journal.pone.0007231