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Upregulation of p16(INK4A) and Bax in p53 wild/p53-overexpressing crypts in ulcerative colitis-associated tumours

In ulcerative colitis (UC)-associated tumours, p53 gene mutations and p53 protein overexpression are frequently found in early stages, but the two types of alteration do not always coincide. To clarify this discrepancy, p53 mutations and expression of p53-associated molecules were analysed in UC-ass...

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Detalles Bibliográficos
Autores principales:	Yoshida, T, Matsumoto, N, Mikami, T, Okayasu, I
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747701/ https://www.ncbi.nlm.nih.gov/pubmed/15292938 http://dx.doi.org/10.1038/sj.bjc.6602050

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