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Reduced Apaf-1 expression in human cutaneous melanomas

Malignant melanoma is a life-threatening skin cancer due to its highly metastatic character and resistance to radio- and chemotherapy. It is believed that the ability to evade apoptosis is the key mechanism for the rapid growth of cancer cells. However, the exact mechanism for failure in the apoptot...

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Detalles Bibliográficos
Autores principales: Dai, D L, Martinka, M, Bush, J A, Li, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747705/
https://www.ncbi.nlm.nih.gov/pubmed/15305193
http://dx.doi.org/10.1038/sj.bjc.6602092