RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer

Cyclooxygenases (particularily Cox-2) are involved in carcinogenesis and metastatic cancer progression. The expression profiles of the cyclooxygenases and the roles they play in established tumours of similar stage remains unclear. We report that Cox-1 and Cox-2 expression is highly variable in Duke...

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Autores principales: Church, R D, Yu, J, Fleshman, J W, Shannon, W D, Govindan, R, McLeod, H L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747709/
https://www.ncbi.nlm.nih.gov/pubmed/15328521
http://dx.doi.org/10.1038/sj.bjc.6602119
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author Church, R D
Yu, J
Fleshman, J W
Shannon, W D
Govindan, R
McLeod, H L
author_facet Church, R D
Yu, J
Fleshman, J W
Shannon, W D
Govindan, R
McLeod, H L
author_sort Church, R D
collection PubMed
description Cyclooxygenases (particularily Cox-2) are involved in carcinogenesis and metastatic cancer progression. The expression profiles of the cyclooxygenases and the roles they play in established tumours of similar stage remains unclear. We report that Cox-1 and Cox-2 expression is highly variable in Dukes' C tumours, and changes in Cox-1 expression may be of importance.
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spelling pubmed-27477092009-09-21 RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer Church, R D Yu, J Fleshman, J W Shannon, W D Govindan, R McLeod, H L Br J Cancer Short Communication Cyclooxygenases (particularily Cox-2) are involved in carcinogenesis and metastatic cancer progression. The expression profiles of the cyclooxygenases and the roles they play in established tumours of similar stage remains unclear. We report that Cox-1 and Cox-2 expression is highly variable in Dukes' C tumours, and changes in Cox-1 expression may be of importance. Nature Publishing Group 2004-09-13 2004-08-24 /pmc/articles/PMC2747709/ /pubmed/15328521 http://dx.doi.org/10.1038/sj.bjc.6602119 Text en Copyright © 2004 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Short Communication
Church, R D
Yu, J
Fleshman, J W
Shannon, W D
Govindan, R
McLeod, H L
RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer
title RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer
title_full RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer
title_fullStr RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer
title_full_unstemmed RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer
title_short RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer
title_sort rna profiling of cyclooxygenases 1 and 2 in colorectal cancer
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747709/
https://www.ncbi.nlm.nih.gov/pubmed/15328521
http://dx.doi.org/10.1038/sj.bjc.6602119
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AT govindanr rnaprofilingofcyclooxygenases1and2incolorectalcancer
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