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CGHnormaliter: an iterative strategy to enhance normalization of array CGH data with imbalanced aberrations

BACKGROUND: Array comparative genomic hybridization (aCGH) is a popular technique for detection of genomic copy number imbalances. These play a critical role in the onset of various types of cancer. In the analysis of aCGH data, normalization is deemed a critical pre-processing step. In general, aCG...

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Detalles Bibliográficos
Autores principales: van Houte, Bart PP, Binsl, Thomas W, Hettling, Hannes, Pirovano, Walter, Heringa, Jaap
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748095/
https://www.ncbi.nlm.nih.gov/pubmed/19709427
http://dx.doi.org/10.1186/1471-2164-10-401