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CGHnormaliter: an iterative strategy to enhance normalization of array CGH data with imbalanced aberrations
BACKGROUND: Array comparative genomic hybridization (aCGH) is a popular technique for detection of genomic copy number imbalances. These play a critical role in the onset of various types of cancer. In the analysis of aCGH data, normalization is deemed a critical pre-processing step. In general, aCG...
Autores principales: | van Houte, Bart PP, Binsl, Thomas W, Hettling, Hannes, Pirovano, Walter, Heringa, Jaap |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748095/ https://www.ncbi.nlm.nih.gov/pubmed/19709427 http://dx.doi.org/10.1186/1471-2164-10-401 |
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