Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity

Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wild-type and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT.

Detalles Bibliográficos
Autores principales: Khunnawutmanotham, Nisachon, Chimnoi, Nitirat, Thitithanyanont, Arunee, Saparpakorn, Patchreenart, Choowongkomon, Kiattawee, Pungpo, Pornpan, Hannongbua, Supa, Techasakul, Supanna
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2009
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748688/
https://www.ncbi.nlm.nih.gov/pubmed/19777131
http://dx.doi.org/10.3762/bjoc.5.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748688/
https://www.ncbi.nlm.nih.gov/pubmed/19777131
http://dx.doi.org/10.3762/bjoc.5.36

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