Binding fullerenol C(60)(OH)(24) to dsDNA

The first C(60)(OH)(24)-DNA complex and its fluorescence enhancement is reported. The enhanced fluorescence intensity of fullerenol C(60)(OH)(24) is in proportion to the concentration of DNA in the range of 1 × 10(−9) to 8 × 10(−5) molL(−1) and the detection limit was 1.3 ng mL(−1). Fullerenol C(60)...

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Detalles Bibliográficos
Autores principales: Pinteala, Mariana, Dascalu, Andrei, Ungurenasu, Cezar
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748842/
https://www.ncbi.nlm.nih.gov/pubmed/19774118
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author Pinteala, Mariana
Dascalu, Andrei
Ungurenasu, Cezar
author_facet Pinteala, Mariana
Dascalu, Andrei
Ungurenasu, Cezar
author_sort Pinteala, Mariana
collection PubMed
description The first C(60)(OH)(24)-DNA complex and its fluorescence enhancement is reported. The enhanced fluorescence intensity of fullerenol C(60)(OH)(24) is in proportion to the concentration of DNA in the range of 1 × 10(−9) to 8 × 10(−5) molL(−1) and the detection limit was 1.3 ng mL(−1). Fullerenol C(60)(OH)(24) binds significantly to the phosphate backbone of native dsDNA and to base-pairs within the major groove of sodium salt of dsDNA.
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spelling pubmed-27488422009-09-22 Binding fullerenol C(60)(OH)(24) to dsDNA Pinteala, Mariana Dascalu, Andrei Ungurenasu, Cezar Int J Nanomedicine Original Research The first C(60)(OH)(24)-DNA complex and its fluorescence enhancement is reported. The enhanced fluorescence intensity of fullerenol C(60)(OH)(24) is in proportion to the concentration of DNA in the range of 1 × 10(−9) to 8 × 10(−5) molL(−1) and the detection limit was 1.3 ng mL(−1). Fullerenol C(60)(OH)(24) binds significantly to the phosphate backbone of native dsDNA and to base-pairs within the major groove of sodium salt of dsDNA. Dove Medical Press 2009 2009-09-10 /pmc/articles/PMC2748842/ /pubmed/19774118 Text en © 2009 Pinteala et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Pinteala, Mariana
Dascalu, Andrei
Ungurenasu, Cezar
Binding fullerenol C(60)(OH)(24) to dsDNA
title Binding fullerenol C(60)(OH)(24) to dsDNA
title_full Binding fullerenol C(60)(OH)(24) to dsDNA
title_fullStr Binding fullerenol C(60)(OH)(24) to dsDNA
title_full_unstemmed Binding fullerenol C(60)(OH)(24) to dsDNA
title_short Binding fullerenol C(60)(OH)(24) to dsDNA
title_sort binding fullerenol c(60)(oh)(24) to dsdna
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748842/
https://www.ncbi.nlm.nih.gov/pubmed/19774118
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AT ungurenasucezar bindingfullerenolc60oh24todsdna

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