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Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials
BACKGROUND: Bisphosphonates might modulate the development of symptomatic bone metastases in men with prostate cancer. The Medical Research Council (MRC) PR05 and PR04 randomised controlled trials assessed the use of sodium clodronate, an oral, first-generation bisphosphonate. We report the final an...
Autores principales: | Dearnaley, David P, Mason, Malcolm D, Parmar, Mahesh KB, Sanders, Karen, Sydes, Matthew R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Lancet Pub. Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748902/ https://www.ncbi.nlm.nih.gov/pubmed/19674936 http://dx.doi.org/10.1016/S1470-2045(09)70201-3 |
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