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Identification of Caspase-mediated Decay of Interferon Regulatory Factor-3, Exploited by a Kaposi Sarcoma-associated Herpesvirus Immunoregulatory Protein

Upon virus infection, the cell mounts an innate type I interferon (IFN) response to limit the spread. This response is orchestrated by the constitutively expressed IFN regulatory factor (IRF)-3 protein, which becomes post-translationally activated. Although the activation events are understood in de...

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Detalles Bibliográficos
Autores principales:	Aresté, Cristina, Mutocheluh, Mohamed, Blackbourn, David J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Transcription, Chromatin, and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749101/ https://www.ncbi.nlm.nih.gov/pubmed/19553679 http://dx.doi.org/10.1074/jbc.M109.033290

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