Cargando…
Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome
Brugada syndrome is a life-threatening, inherited arrhythmia disorder associated with autosomal dominant mutations in SCN5A, the gene encoding the human cardiac Na(+ )channel α subunit (Nav1.5). Here, we characterized the biophysical properties of a novel Brugada syndrome-associated Nav1.5 mutation,...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749822/ https://www.ncbi.nlm.nih.gov/pubmed/19706159 http://dx.doi.org/10.1186/1423-0127-16-76 |