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Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells
BACKGROUND: In addition to their well-documented ocular therapeutic effects, glucocorticoids (GCs) can cause sight-threatening side-effects including ocular hypertension presumably via morphological and biochemical changes in trabecular meshwork (TM) cells. In the present study, we directly compared...
Autores principales: | Nehmé, Alissar, Lobenhofer, Edward K, Stamer, W Daniel, Edelman, Jeffrey L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749862/ https://www.ncbi.nlm.nih.gov/pubmed/19744340 http://dx.doi.org/10.1186/1755-8794-2-58 |
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